Effectiveness of 20% Olive Cream in Reducing Skin Dryness in Chronic Kidney Disease Patients

Chronic Kidney Disease on Hemodialysis (CKD-HD) is still at a high prevalence, with xerosis cutis as its major dermatologic complication. To find the proper alternative therapy for this case, olive cream can be an option because they have been proven to reduce skin dryness. This study compares the effectiveness and safety of olive cream 20% in reducing skin dryness in CKD-HD patients. A randomized controlled trial involved 35 eligible CKD-HD patients. Each subject was given an intervention using olive cream 20% and urea cream 20% as control on the front lower leg for 4 weeks. Overall dry skin (ODS) and corneometer scores were measured and compared weekly. Both the olive cream 20% and urea cream 20% groups showed a statistically significant increase in corneometer score during the treatment period (p < 0.001), with a similar increase in score across each week of observation. Additionally, both groups demonstrated a statistically significant decrease in ODS value during the treatment period (p < 0.001), with a similar decrease in value across each week of observation. No side effects were found in either group. Olive cream 20% and urea cream 20% have similar efficacy and safety in improving xerosis cutis in CKD-HD patients. These results not only support the use of olive cream 20% as an alternative in this study but its potential to become a preferred treatment option.